The document summarizes the key developments in mining and settlement in the American West between 1850-1900. It describes how the discovery of gold and silver in places like Virginia City led to boomtowns. Technological advances like barbed wire, steel plows and windmills helped enable large-scale farming on the plains. The Homestead Act of 1862 encouraged western expansion by offering settlers land. The completion of the Transcontinental Railroad in 1869 further transformed the region. However, this influx of settlers and depletion of buffalo herds by hunters caused conflicts with Native Americans over land, leading to events like the Battle of Little Bighorn and Wounded Knee Massacre.